Use of RADIESSE® in the dorsum of the hand may result in significant swelling of the dorsum of the hand.

Tell your doctor if you are pregnant, intending to become pregnant, or breastfeeding before being administered Botox because it may not be suitable for you.

Depending on patient symptoms, institute catheterization if PVR urine volume exceeds 200 mL and continue until PVR falls below 200 mL. Instruct patients to contact their physician if they experience difficulty in voiding as catheterization may be required.

Instructions for the Minor’s Iodine-Starch Test Procedure: Patients should shave underarms and abstain from use of over-the-counter deodorants or antiperspirants for 24 hours prior to the test. Patient should be resting comfortably without exercise or hot drinks for approximately 30 minutes prior to the test. Dry the underarm area and then immediately paint it with iodine solution.

Before receiving Botox, tell your healthcare provider about all your medical conditions, including if you:

Dosing in initial and sequential treatment sessions should be tailored to the individual based on the size, number and location of muscles involved, severity of spasticity, the presence of local muscle weakness, the patient’s response to previous treatment, or adverse event history with BOTOX.

Botox should only ever be injected by a licensed provider. Do NOT attempt to inject this at home yourself as serious and potentially life-threatening side effects may occur. Licensed providers use a thin needle to inject Botox into the targeted muscle or gland.

Limitations of Use BOTOX has not been shown to improve upper extremity functional abilities, or range of motion at a joint affected by a fixed contracture. 1.5 Cervical Dystonia

The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have an underlying condition that would predispose them to these symptoms. In unapproved uses and in approved indications, cases of spread of effect have been reported at doses comparable to those used to treat cervical dystonia and spasticity and at lower doses [see Warnings and Precautions (5.1)].

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

In adult spasticity patients with reduced lung function, upper respiratory tract infections were also reported more frequently as adverse reactions in patients treated with BOTOX than in patients treated with placebo [see Warnings and Precautions (5.10)].

Physicians administering BOTOX must understand the relevant neuromuscular and structural anatomy of the area involved liftera and any alterations to the anatomy due to prior surgical procedures and disease, especially when injecting near the lungs.

If a local anesthetic instillation is performed, the bladder should be drained and irrigated with sterile saline before injection.

Because clinical trials are conducted under widely varying conditions, the adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.